Antibody-Drug Conjugates
Laurent Ducry
Antibody-drug conjugates (ADCs) represent a promising therapeutic approach for cancer patients by combining the antigen-targeting specificity of monoclonal antibodies (mAbs) with the cytotoxic potency of chemotherapeutic drugs. In Antibody-Drug Conjugates, expert researchers provide detailed protocols for many of the key ADC techniques necessary for working in the field. These chapters and methodologies are aimed at the key tasks necessary to identify a suitable target, properly design the mAb, the linker and the payload, as well as to conjugate them in a reproducible and scalable fashion. Written in the highly successful Methods in Molecular BiologyTM format, these detailed chapters include the kind of practical implementation advice that guarantees quality results. Authoritative and timely, Antibody-Drug Conjugates aims to further drive ADC development and thus help toward improving cancer treatments of the future.
Catégories:
Volume:
1045
Année:
2013
Edition:
1st
Editeur::
Humana Press
Langue:
english
Pages:
317
ISBN 10:
1627035419
ISBN 13:
9781627035415
Collection:
Methods in Molecular Biology
Fichier:
PDF, 5.98 MB
IPFS:
,
english, 2013